Response Prediction to Methylphenidate in ADHD
نویسندگان
چکیده
منابع مشابه
Predicting Methylphenidate Response in ADHD Using Machine Learning Approaches.
BACKGROUND There are no objective, biological markers that can robustly predict methylphenidate response in attention deficit hyperactivity disorder. This study aimed to examine whether applying machine learning approaches to pretreatment demographic, clinical questionnaire, environmental, neuropsychological, neuroimaging, and genetic information can predict therapeutic response following methy...
متن کاملADHD, Methylphenidate, and Childhood Epilepsy
Investigators from the Department of Functional Neurology, Epileptology and Epilepsy Institute (IDEE), and the Lyon's University Hospital examined the clinical determinants of ADHD severity in children with epilepsy (CWE) along with the response to treatment with methylphenidate (MPH).
متن کاملResponse to methylphenidate in adults with ADHD is associated with a polymorphism in SLC6A3 (DAT1).
In this pharmacogenetic study in adults with ADHD (n = 42), a stratified analysis was performed of the association between response to methylphenidate (MPH), assessed under double-blind conditions, and polymorphisms in the genes encoding the dopamine transporter, SLC6A3 (DAT1), the norepinephrine transporter, SLC6A2 (NET), and the dopamine receptor D4, DRD4. The VNTR polymorphism in the 3' untr...
متن کاملExocytosis-related genes and response to methylphenidate treatment in adults with ADHD.
Experimental studies have demonstrated that methylphenidate (MPH) modulates the synaptic vesicle trafficking and synaptotagmin-1 (SytI) mRNA levels. SytI is a regulatory protein of the SNARE complex, a neurotransmitter exocytosis mediator. Despite this evidence, most SNARE complex-related genes have never been evaluated in attention-deficit/hyperactivity disorder (ADHD) pharmacogenetics. This s...
متن کاملMethylphenidate and growth in ADHD children
Attention deficit hyperactivity disorder (ADHD) is a group of developmental disorder characterized by developmentally-inappropriate levels of over activity, inattention and impulsivity. The most common treatment of ADHD is medication with stimulants, by specific methylphenidate which has been shown to improve attention and behavior. The treatment by stimulants may be accompanied by side effects...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 1995
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-9-8-12